De-Intensification from Basal-Bolus Insulin Therapy to Liraglutide in Type 2 Diabetes: Predictive Value of Mean Glycaemia during Fasting Test.

Background: Successful conversion from insulin therapy to glucagon-like peptide 1 receptor agonist (GLP-1RA) with basal insulin in well-controlled patients has already been demonstrated. However, the data concerning individuals with poor glycaemic control are scarce. The aim of this work was to assess the success rate of insulin therapy to liraglutide transition in poorly controlled diabetes in a real-world clinical setting and to define predictors of success.

Alpha-gal Syndrome - A Case Report of Tick-Borne Anaphylactic Shock.

Unlabelled: The most common cause of vasoplegic shock in critical care is sepsis. However, although rarely and only in specifically sensitised individuals previously bitten by a tick, red meat may provoke a delayed allergic reaction called an alpha-gal syndrome. We present a case of a protracted life-threatening manifestation of alpha-gal syndrome, which, due to an unusual absence of typical features of anaphylaxis can masquerade as septic shock and calls attention to the premature diagnostic closure as a contributor to diagnostic error.

Pregnancy outcomes in women with a hemoglobinopathy trait: a multicenter, retrospective study.

Purpose: To determine the risk of adverse maternal and neonatal outcomes in pregnant women with a hemoglobinopathy trait.

Materials And Methods: Retrospective cohort study was conducted to compare adverse maternal and neonatal outcomes between pregnant women with a hemoglobinopathy trait (study group; n = 172), and without a hemoglobinopathy trait (control group; n = 360). The medical data were extracted from clinical records of pregnant women attending antenatal care and delivering at the University Hospital Basel or University Hospital Zurich between 2015 and 2018.

Parameters of the wave M in 398 patients with tetanic syndrome proved with positive ischemic or hyperventilation tests.

398 patients with clinical signs of tetanic syndrome were examined. Their ischemic and/or hyperventilation tests were positive. The parameters of the wave M were analysed i.