Machine-designed biotherapeutics: opportunities, feasibility and advantages of deep learning in computational antibody discovery.

Antibodies are versatile molecular binders with an established and growing role as therapeutics. Computational approaches to developing and designing these molecules are being increasingly used to complement traditional lab-based processes. Nowadays, in silico methods fill multiple elements of the discovery stage, such as characterizing antibody-antigen interactions and identifying developability liabilities.

Mutually unbiased bases and symmetric informationally complete measurements in Bell experiments.

Mutually unbiased bases (MUBs) and symmetric informationally complete projectors (SICs) are crucial to many conceptual and practical aspects of quantum theory. Here, we develop their role in quantum nonlocality by (i) introducing families of Bell inequalities that are maximally violated by -dimensional MUBs and SICs, respectively, (ii) proving device-independent certification of natural operational notions of MUBs and SICs, and (iii) using MUBs and SICs to develop optimal-rate and nearly optimal-rate protocols for device-independent quantum key distribution and device-independent quantum random number generation, respectively. Moreover, we also present the first example of an extremal point of the quantum set of correlations that admits physically inequivalent quantum realizations.

Self-Testing Entangled Measurements in Quantum Networks.

Self-testing refers to the possibility of characterizing an unknown quantum device based only on the observed statistics. Here we develop methods for self-testing entangled quantum measurements, a key element for quantum networks. Our approach is based on the natural assumption that separated physical sources in a network should be considered independent.

A universal test for gravitational decoherence.

Quantum mechanics and the theory of gravity are presently not compatible. A particular question is whether gravity causes decoherence. Several models for gravitational decoherence have been proposed, not all of which can be described quantum mechanically.

Analytic and Nearly Optimal Self-Testing Bounds for the Clauser-Horne-Shimony-Holt and Mermin Inequalities.

Self-testing refers to the phenomenon that certain extremal quantum correlations (almost) uniquely identify the quantum system under consideration. For instance, observing the maximal violation of the Clauser-Horne-Shimony-Holt (CHSH) inequality certifies that the two parties share a singlet. While self-testing results are known for several classes of states, in many cases they are only applicable if the observed statistics are almost perfect, which makes them unsuitable for practical applications.