Publications by authors named "J Kamei"
Background: Dose-dense methotrexate, vinblastine, doxorubicin, and cisplatin (dd-MVAC) regimen has been established as a systemic chemotherapy for patients with urothelial carcinoma. However, it is rarely used in Japan owing to the challenges associated with managing the related adverse events. This study aimed to optimize the dd-MVAC protocol for Japanese patients.
View Article and Find Full Text PDFIntroduction Lymphocele is a typical complication of pelvic lymph node dissection (PLND) in robot-assisted radical prostatectomy (RARP). This study aimed to compare postoperative lymphatic leakage between the polymer ligation clip and vessel sealer, and evaluated the costs associated with the former. Methods The study enrolled patients who underwent RARP with PLND at our institution between April 2018 and March 2023 and were treated with a vessel sealer (LigaSure Blunt Tip 44 NC; Medtronic, Dublin, Ireland) until September 2021, and Hem-o-lok polymer ligation clips(Teleflex, Wayne, PA, USA) thereafter.
View Article and Find Full Text PDFArticle Synopsis
- A study reviewed 106 patients with advanced urothelial carcinoma treated with the antibody-drug conjugate enfortumab vedotin (EV) between 2021 and 2023 to evaluate the impact of treatment-related adverse events (trAEs) on survival outcomes.* -
- The results indicated that 88.7% of patients experienced some form of trAEs, with skin and gastrointestinal issues being the most common, and a landmark analysis suggested that trAEs were linked to longer overall survival, particularly physical trAEs.* -
- The study concluded that managing trAEs and understanding their prognostic value is important for improving the outcomes of EV therapy in these patients, highlighting that physical trAEs were
Objective: Surgical treatment for renal cell carcinoma (RCC) has drastically evolved for the past 30 years. However, survival outcomes of RCC according to times have not been fully elucidated, especially in the real-world setting. This study aimed to assess the survival improvement over time in RCC treated with nephrectomy by analyzing a longitudinal cohort using propensity score matching (PSM).
View Article and Find Full Text PDFBackground: The aim of this study is to describe the first series of six patients undergoing Retzius-sparing robot-assisted radical prostatectomy (rs-RARP) using the hinotori surgical robot system (hinotori SRS) and to compare the treatment outcomes with those achieved with the da Vinci surgical platform.
Methods: This study included 20 cases involving the rs-RARP procedure (hinotori: N = 6; da Vinci: N = 14) that were performed between May 2021 and April 2024 in a single institution.
Results: No significant differences were observed between the hinotori and da Vinci groups regarding the preoperative findings.