Publications by authors named "J Kalita"
Glucose-dependent insulin delivery systems have been recognized as a promising approach for controlling blood sugar levels in individuals with diabetes mellitus (DM). Recently, titanium dioxide nanoparticles have garnered huge attention in scientific research for their small size and effective drug delivery capabilities. In this study, we developed alizarin (AL)-capped phenylboronic acid (PBA)-functionalized titanium dioxide nanoparticles (TiO) for glucose-sensitive insulin delivery (TiO-PBA-INS-AL) aiming to manage both blood sugar levels and its associated organ pathology in DM.
View Article and Find Full Text PDFThe cardinal clinical features of complex regional pain syndrome type I (CRPS-I) are pain, edema, autonomic changes, and limitation of motoric movement, which may indicate the role of inflammation and cytokines. We report the effect of prednisolone on the clinical severity and mRNA profiling of proinflammatory (tumor necrosis factor (TNF)-α and interleukin (IL)-2) and anti-inflammatory cytokines (IL-10 and transforming growth factor (TGF)-β) in the patient with CRPS-I. Thirty-nine patients with CRPS-I of shoulder joint were enrolled.
View Article and Find Full Text PDFBackground: Tenecteplase has been approved for acute ischemic stroke at a dose of 0.2 mg/kg by the Indian licensing authority. A registry to evaluate the safety of tenecteplase was mandated by the licensing authority.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates how hope acts as a coping mechanism and utilizes Natural Language Processing (NLP) tools to analyze social media posts about hope, focusing on psycholinguistic and emotional features.
- It identifies various cognitive and emotional characteristics associated with different types of hope expressed online and explores the potential to classify these types using machine learning algorithms.
- Models like LightGBM and CatBoost were found to outperform traditional methods, showing notable improvements in efficiency through hyperparameter tuning.
Article Synopsis
- The study investigates the recovery patterns of different neurological functions in Guillain-Barré Syndrome (GBS), focusing on facial, bulbar, sensory, motor, and autonomic dysfunctions.
- It included 42 GBS patients, tracking their recovery over three months, noting that autonomic functions recovered the fastest, while normal motor function was less common within the follow-up period.
- Results showed that recovery times for bulbar and sensory functions were quicker in patients with the demyelinating form (AIDP) compared to the axonal form (AMAN), highlighting a consistent trend of recovery across both types of GBS.