Publications by authors named "J KRATOCHVIL"

This study demonstrates the use of nanoparticles prepared by a gas aggregation source for fabricating structures by combining laser sintering and ablation. At first, the morphology and optical properties of prepared nanoparticle coatings were characterized. Then, the response of coatings to laser irradiation at different powers or exposure times was studied by in situ time-of-flight mass spectrometry, followed by scanning electron microscopy measurements of the resulting structures.

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Mass photometry (MP) is a rapidly growing optical technique for label-free mass measurement of single biomolecules in solution. The underlying measurement principle provides numerous advantages over ensemble-based methods but has been limited to low analyte concentrations due to the need to uniquely and accurately quantify the binding of individual molecules to the measurement surface, which results in diffraction-limited spots. Here, we combine nanoparticle lithography with surface PEGylation to substantially lower surface binding, resulting in a 2 orders of magnitude improvement in the upper concentration limit associated with mass photometry.

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Article Synopsis
  • Researchers explored solid-state 2 µm lasers using thulium-doped materials (Tm:YAG, Tm:YAP, Tm:YLF) with 1.7 µm resonant diode pumping instead of the usual 0.8 µm.
  • They achieved a high slope efficiency of up to 80% for Tm:YAP and Tm:YLF, nearing the quantum limit without depending on Tm-Tm cross-relaxation energy transfer.
  • The low thermal load enabled stable continuous-wave operation with excellent beam quality and output power reaching up to 6 W for Tm:YAG/Tm:YLF and 8 W for Tm:YAP.
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Double strap lap adhesive joints between metal (AA 6061-T6) and composite (carbon/epoxy) laminates were fabricated and characterized based on strength. Hand layup methods were used to fabricate double strap match lap joints and double strap mismatch lap joints. These joints were compared for their strength under static and fatigue loadings.

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The finite element analysis technique was used to investigate the suitability of silver nanorods, spheres, ellipsoids and core−shell structures for the hyperthermia treatment of cancer. The temperature of the silver nanostructures was raised from 42 to 46 °C, in order to kill the cancerous cells. The time taken by the nanostructures to attain this temperature, with external source heating, was also estimated.

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