Publications by authors named "J K Thakkar"

Article Synopsis
  • Cardiorespiratory signals, previously considered noise in fMRI research, are now recognized for their potential insights into brain function and health.
  • These signals, including heart rate variability and respiratory patterns, reflect the interaction between cardiovascular, respiratory, and neural systems that support brain activity.
  • Understanding these signals can improve fMRI data interpretation, highlighting the connections between heart, brain, and overall physiological health.
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  • - The Green Revolution aims to increase food production in India but has negative impacts on health and agriculture; natural manures like cow dung can help mitigate these issues by enhancing soil quality and crop yield.
  • - Zero Budget Natural Farming (ZBNF) practices, particularly with Jivamrit, promote healthier soils and contain essential nutrients while fostering beneficial microbes that improve plant growth.
  • - While Jivamrit uses natural substances to boost sustainable agriculture, long-term reliance on it could upset the microbial balance in the soil, underlining the need for careful management of agricultural practices.
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  • Wernicke encephalopathy (WE) can lead to various neuro-ophthalmic symptoms like vision loss, and this case highlights a 53-year-old woman who experienced bilateral painless vision decline alongside other neurological issues.* -
  • Despite elevated inflammatory markers and a thorough work-up revealing no clear cause, brain MRI indicated possible WE, prompting immediate high-dose thiamine treatment, which led to significant improvement.* -
  • The case stresses the importance of considering vision loss in Wernicke-Korsakoff syndrome (WKS) patients and suggests that while checking thiamine levels is important, starting treatment based on clinical suspicion is often necessary and safe.*
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Article Synopsis
  • * The study identified that certain diabetes-associated genes are highly expressed in hormone-receptor-positive (HR+) breast cancer cells and correlated with poorer survival outcomes in breast cancer patients.
  • * Metformin, a medication for T2D, was shown to significantly reduce tumor growth in HR+ breast cancer cells and, when combined with tamoxifen, may offer a promising new treatment strategy for affected patients.
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