Publications by authors named "J K Tambascia"
Article Synopsis
- The study investigated the link between clue cells in cervical smears and COX-2 expression in cervical intraepithelial neoplasia (CIN) lesions, analyzing samples from 228 women.
- Out of these, the majority had CIN3, and the prevalence of clue cells was similar across different CIN severities, but there was a noticeable negative association between COX-2 expression and the presence of clue cells in Pap smears.
- Additionally, while HPV infection showed a borderline association with COX-2 expression, the research suggests that clue cells might disrupt the inflammatory processes related to the development of CIN.
Cervical cancer screening remains a challenge in developing countries due to a complex array of problems. This paper aimed to describe the experience with organization of cervical cancer screening in three districts of Campinas and the surrounding region in São Paulo State, Brazil, and to report the resulting data. The program was organized in a pyramid format, and the health care hierarchy was defined according to the complexity and total number of medical procedures.
View Article and Find Full Text PDFObjective: We compared the performance of cervical cytology and HPV DNA test in detection of residual or recurrent disease following the treatment of cervical intraepithelial neoplasia (CIN) 2/3 with loop electrosurgical excision procedure (LEEP).
Subjects And Methods: A series of 107 women subjected to LEEP due to histologically confirmed CIN 2/3 between March 2001 and December 2002 were followed-up biannually until January 2004. Follow-up visits consisted of interview and gynecological examination including cervical cytology, hybrid capture II (HCII), and colposcopy.
Objective: The study was designed to compare the Pap smear results, performed on the public health service, with: the results of Pap smear collected on the reference service; the colposcopy and punch biopsy results.
Methods: The total of 213 women assisted at the women's hospital from January 1989 to April 1991, and followed until July 1998 were selected. Ninety were referred because a Pap smears suggestive of Human Papillomavirus (HPV) induced lesion or cervical intraepithelial neoplasia (CIN) grade 1, and 123, CIN 2 or 3.
A fine needle aspiration biopsy (FNAB) device was designed to utilize a steel spring located between the syringe and its plunger, which exerts a constant negative pressure (auto-vacuum). In 43 rats inoculated with breast tumour cells, the technique was compared with the standard procedure of FNAB (21 Sp1 and 22 Walker256 carcinosarcoma). Malignant cells were cytologically confirmed in all cases.
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