Genome-informed Discovery of Monchicamides A-K: Cyanobactins from the Microcoleaceae Cyanobacterium LEGE 16532.

Genome mining has emerged as an important tool for the discovery of natural products and is particularly effective for the swift identification of ribosomally synthesized and post-translationally modified peptides (RiPPs). Among RiPPs, cyanobactins have gained attention due to their diverse structures and bioactive properties. Here, we explored the Microcoleaceae cyanobacterium LEGE 16532 strain and identified the biosynthetic gene cluster (BGC), which was predicted to encode cyanobactin-like molecules.

Mild hypohydration in healthy older adults increases pain-related brain activity without affecting pain perception: A single-blind study.

Understanding how hydration status influences pain perception is particularly important in older adults, as both dehydration and pain are prevalent in this population. Ten individuals (70 ± 4 years) completed two randomized and counterbalanced trials. They were exposed to passive heat until they lost 1% body mass through sweat and urine (~ 100 min), with the loss either unreplaced (sham infusion, HYPO) or fully replaced via 0.

Taxonomic revision of Entomobrya Rondani, 1861 (Collembola: Entomobryidae: Entomobryinae) from the Brazilian Amazon.

Herein, the species of Entomobrya Rondani from the Brazilian Amazon are reviewed. Entomobrya paroara Arlé & Guimarães, E. egleri Arlé & Guimarães and E.

Determinants of First Practice Location among Canadian Geriatric Medicine Trainees and Recent Graduates: Findings of a Cross-sectional Survey in 2023.

Background: There is a projected and growing gap of geriatricians in Canada. Geriatricians play a crucial role in addressing the health needs of older adults. We aimed to understand the factors that influence the choice of first-practice location for new geriatricians in the context of an aging Canadian population.

Incorporation of mixed strawberry and acerola jam into Greek-style goat yogurt with autochthonous adjunct culture of Limosilactobacillus mucosae CNPC007: Impact on technological, nutritional, bioactive, and microbiological properties.

This study aimed to assess the impact of adding strawberry and acerola jam, along with Limosilactobacillus mucosae CNPC007, on the technological, nutritional, bioactive, and microbiological properties of Greek-style goat yogurt. Six yogurt formulations were developed: without and with the addition of L. mucosae CNPC007 (CY and PY, respectively), and with 10 % and 15 % jam (CY10, CY15, PY10, and PY15, respectively).