Publications by authors named "J K Makin"
Article Synopsis
- * This study explores whether ANNs can also predict spiking activity in auditory neurons at finer time scales (50 ms and below) by using recordings from the auditory cortex of squirrel monkeys reacting to speech audio and monkey vocalizations.
- * Results show that trained ANN layers can explain a significant portion of neural variance in responses, particularly with non-primary neurons being more predictable by deeper layers, highlighting individual neuron variability that isn't captured by standard recording techniques.
Background: This systematic review and meta-analysis seeks to investigate the effectiveness and safety of manual therapy (MT) interventions compared to oral pain medication in the management of neck pain.
Methods: We searched from inception to March 2023, in Cochrane Central Register of Controller Trials (CENTRAL), MEDLINE, EMBASE, Allied and Complementary Medicine (AMED) and Cumulative Index to Nursing and Allied Health Literature (CINAHL; EBSCO) for randomized controlled trials that examined the effect of manual therapy interventions for neck pain when compared to medication in adults with self-reported neck pain, irrespective of radicular findings, specific cause, and associated cervicogenic headaches. We used the Cochrane Risk of Bias 2 tool to assess the potential risk of bias in the included studies, and the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) approach to grade the quality of the evidence.
The proliferation of multi-unit cortical recordings over the last two decades, especially in macaques and during motor-control tasks, has generated interest in neural 'population dynamics': the time evolution of neural activity across a group of neurons working together. A good model of these dynamics should be able to infer the activity of unobserved neurons within the same population and of the observed neurons at future times. Accordingly, Pandarinath and colleagues have introduced a benchmark to evaluate models on these two (and related) criteria: four data sets, each consisting of firing rates from a population of neurons, recorded from macaque cortex during movement-related tasks.
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- - The study focuses on improving the availability of safe blood for patients in low-resource settings like Kenya, addressing issues like low blood donation rates and inefficient testing procedures.
- - It employs a mixed-methods approach, utilizing qualitative interviews and quantitative data to analyze the blood supply chain and identify community-driven interventions within differing socioeconomic contexts.
- - The goal is to create a comprehensive process map of the blood system and determine which policy and environmental changes could most effectively enhance blood transfusion availability, particularly considering various levels of urgency.