Introduction: Paranoid ideation is a relatively common experience in adolescence, yet it has not been well-explored in relation to psychological well-being and functioning in general population samples of youth. The current study aimed to investigate the relations between paranoia (operationalized as "persecutory ideation"), well-being, and two domains of functioning, social (e.g.
View Article and Find Full Text PDFThe drug development landscape is expanding to include drug modalities such as PROteolysis-TArgeting Chimeras (PROTACs) and peptides, offering possibilities for previously intractable biological targets. However, with their size and chemical nature, they diverge from established frameworks for the prediction of oral bioavailability. This evolution to larger and more complex molecules necessitates new methodologies and prediction models to continuously expand on bioavailability guidelines.
View Article and Find Full Text PDFResearch on paranoid beliefs in adolescents is in its infancy. Valid and reliable assessments are essential to advancing the field, yet there is no current consensus as to which are optimal to use in this population. This study compared the psychometric properties of two measures of paranoia in a general population adolescent sample.
View Article and Find Full Text PDF