Publications by authors named "J K Harcourt"
Ménière's disease is a disabling condition causing vertigo and hearing loss yet remains incompletely understood. Registry studies have the potential to answer important questions about phenotypes and natural history of clinical conditions. The aim of this study was to explore the feasibility of a patient-centered national Ménière's disease registry.
View Article and Find Full Text PDFArticle Synopsis
- * The CDC's National SARS-CoV-2 Strain Surveillance (NS3) program analyzed SARS-CoV-2 samples to understand the evolution of these variants and their spike mutations from May 2021 to February 2023.
- * The study found that some subvariants have significantly evaded neutralizing antibodies from post-vaccination sera, indicating a need for ongoing research to evaluate the effectiveness of current vaccines and inform future updates.
Article Synopsis
- Prolonged SARS-CoV-2 infections may pose a risk for the development of mutated variants, particularly in immunocompromised individuals, but the specific types of immunosuppressive conditions that increase this risk have not been extensively studied.
- A study conducted across five US medical centers involved 150 immunocompromised patients to identify factors contributing to extended SARS-CoV-2 infections through regular testing and genetic sequencing.
- Results showed that patients with B-cell dysfunction and those who had solid organ transplants or HIV had longer durations of infection compared to those with autoimmune conditions, indicating varying risks based on the type of immunosuppression.
Objective: To identify distinct clinical subtypes of Ménière's disease by analyzing data acquired from a UK registry of patients who have been diagnosed with Ménière's disease.
Study Design: Observational study.
Methods: Patients with Ménière's disease were identified at secondary/tertiary care clinics.
Notes from the Field: Early Identification of the SARS-CoV-2 Omicron BA.2.86 Variant by the Traveler-Based Genomic Surveillance Program - Dulles International Airport, August 2023.
Stephen M Bart Andrew P Rothstein Casandra W Philipson Teresa C Smith Birgitte B Simen Jennifer L Harcourt
MMWR Morb Mortal Wkly Rep
October 2023