Publications by authors named "J K Cheon"
Background: Numerous studies have explored the role of vitamin D in various cancers; however, its impact on advanced biliary tract cancers (BTC) within a prospective cohort remains to be investigated. This preplanned subgroup analysis of the NIFTY trial evaluated the prognostic implications of serum vitamin D levels in patients with advanced BTC undergoing second-line chemotherapy.
Methods: From the 174 patients in the NIFTY trial, a total of 173 patients (99.
Cryotherapy is widely used in veterinary medicine to manage pain and swelling, yet optimal methods for specific tissue depths remain unclear. Cryotherapy modalities, including cold packs (CPs), cold compression (CC), and hyperbaric gaseous cryotherapy (HGC), were applied to nine beagle dogs under general anaesthesia. A custom 3D-printed guide facilitated consistent and accurate measurements of tissue temperatures at depths of 1 and 3 cm.
View Article and Find Full Text PDFPurpose: To compare graft remodeling, as measured by magnetic resonance imaging (MRI), and clinical outcomes between patients who underwent isolated anterior cruciate ligament reconstruction (ACLR) versus combined anterior cruciate ligament and anterolateral ligament reconstruction (ACLR + ALLR).
Methods: A retrospective review was conducted on patients who underwent primary ACLR with quadruple hamstring grafts between January 2019 and March 2022, with a minimum follow-up period of 2 years. Patients were categorized into two groups based on the addition of ALLR with tibialis anterior allografts: an isolated ACLR group and an ACLR + ALLR group.
Recent research highlights the critical role of inflammation in accelerating amyloid beta and phosphorylated tubulin-associated protein tau cascade and Alzheimer's disease (AD) progression. Emerging evidence suggests that exercise influences AD by modulating inflammatory responses. We conducted a comprehensive search across multiple online databases.
View Article and Find Full Text PDFArticle Synopsis
- A study investigated genetic variants linked to nonhereditary colorectal polyposis, focusing on 638 patients without known hereditary mutations, using data collected from 2012 to 2021.
- Genome-wide association study (GWAS) found 71 new single-nucleotide polymorphisms (SNPs) that are potential risk factors for this condition, highlighting five significant genes related to colorectal cancer and introducing two previously unlinked genes.
- Among the identified SNPs, three were notably associated with a higher risk of polyp recurrence, with the gene ABCC4 being particularly significant for nonhereditary colorectal polyposis.