Axis II psychopathology in individuals with traumatic brain injury.

Primary Objectives: To determine the frequency and nature of post-TBI personality disorders (PDs) in a community-based sample of individuals with TBI.

Research Design: One hundred individuals with TBI were administered a structural clinical interview to determine Axis II psychopathology. METHODS OF PROCEDURES: The Structured Clinical Interview for DSM-IV Personality Disorders, Clinician Version (SCID II) was used to determine 12 Axis II personality disorders.

The Beck Depression Inventory: is it a suitable measure of depression for individuals with traumatic brain injury?

Objective: This study examined the relationship between Beck Depression Inventory (BDI) scores and current diagnosis of depression, based on The Structured Clinical Interview for DSM-IV Diagnosis (SCID).

Design: Correlation.

Setting: Community-based sample.

Axis I psychopathology in individuals with traumatic brain injury.

Objectives: To assess the incidence, comorbidity, and patterns of resolution of DSM-IV mood, anxiety, and substance use disorders in individuals with traumatic brain injury (TBI).

Design: The Structured Clinical Interview for DSM-IV Diagnoses (SCID) was utilized. Diagnoses were determined for three onset points relative to TBI onset: pre-TBI, post-TBI, and current diagnosis.

Increased numbers of mast cells in human middle ear cholesteatomas: implications for treatment.

Hypothesis: Because many of the biologic phenomena in which mast cells are involved also are observed in human cholesteatoma pathology, the authors hypothesized that mast cells may play a role in this disease. The first test of this hypothesis is to determine whether there are an increased number of mast cells associated with cholesteatomas.

Background: The molecular and cellular defects that result in the pathologic features observed in acquired and congenital cholesteatomas are unknown.

Expression of p53 protein in human middle ear cholesteatomas: pathogenetic implications.

Background: Cholesteatoma is a destructive lesion of the middle ear or mastoid process or both. The molecular and cellular defects that result in the clinical hallmarks of acquired and congenital cholesteatomas, namely invasion, migration, uncoordinated proliferation, altered differentiation, aggressiveness, and recidivism, are unknown. Determining the existence of defects in the normal biology, biochemistry, and genetic complement of the major cellular constituents comprising a cholesteatoma (i.