Publications by authors named "J Joshua Yune"

Unplanned readmission to intensive care units (UR-ICU) in trauma is associated with increased hospital length of stay and significant morbidity and mortality. We identify independent predictors of UR-ICU and construct a nomogram to estimate readmission probability. We performed an IRB-approved retrospective case-control study at a Level I trauma center between January 2019 and December 2021.

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Background: Better means of identifying patients with increased cardiac complication (CC) risk is needed. Coronary artery calcification (CAC) is reported on routine chest CT scans. We assessed the correlation of CAC and CCs in the geriatric trauma population.

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Objective: Sous-vide cooking offers several advantages for poultry meat, including enhanced tenderness, reduced cooking loss, and improved product yield. However, in duck meat, there are challenges associated with using the sous-vide method. The prolonged cooking time at low temperatures can lead to unstable microbial and oxidative stabilities.

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The ideal treatment option for immature necrotic permanent teeth is regeneration of the pulp-dentin complex. Mineral trioxide aggregate (MTA), the conventional cement used for regenerative endodontic procedures, induces hard tissue repair. Various hydraulic calcium silicate cements (HCSCs) and enamel matrix derivative (EMD) also promote osteoblast proliferation.

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Article Synopsis
  • The study investigates the role of the hydrophobic N-terminal segment in diacylglycerol kinase ε (DGKε), an enzyme involved in the phosphatidylinositol (PI) cycle, by utilizing both computational and experimental methods.
  • Findings reveal that this segment anchors DGKε to the membrane through a transmembrane α-helix and influences its enzymatic activity by modulating the relationship between the enzyme's active site and the membrane-water interface.
  • Additionally, the research concludes that the conserved N-terminal segment significantly affects DGKε's activity and sensitivity to certain membrane properties, highlighting its importance in regulating the enzyme's function during the PI cycle.
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