Publications by authors named "J Jores"
Complete genome sequence of the first strain isolated from a red fox () in Germany.
Microbiol Resour Announc
January 2025
The zoonotic pathogen is part of the oral microbiome of dogs and cats. We report the genome sequence of strain KM3195_24, isolated from a red fox. It has a circular genome of 2,718,701 bp with a G + C content of 36%, 2,419 CDS, 3 rRNA operons, and 45 tRNAs.
View Article and Find Full Text PDFWesselsbron virus (WSLV) is a zoonotic, mosquito-borne orthoflavivirus endemic to sub-Saharan Africa, causing abortions and stillbirths in small ruminants. The life cycle of WSLV involves Aedes mosquitoes and various wildlife and domestic animals. Seminal studies in the 1950s have shown the zoonotic potential of WSLV, notably in accidental infections of laboratory workers exposed to infected material.
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- - Approved vaccines are good for preventing severe COVID-19, but new variants and transmission need a stronger immune response, leading to the creation of modified live-attenuated vaccines (LAVs) that recode the SARS-CoV-2 genome.
- - The new vaccines, called OTS-206 and OTS-228, are designed to be safe and effective, with OTS-228 showing no side effects or transmission in animal studies, and can be given intranasally.
- - A single dose of OTS-228 not only provides strong immunity against the original SARS-CoV-2 strain but also offers broad protection against variants like Omicron, making this approach potentially valuable for other emerging viruses as well. *
Zebu cattle (Bos indicus) is reported to be more resistant towards harmful environmental factors than taurine cattle (Bos taurus). A few hundred zebu cattle are kept in Switzerland and in contrast to the Swiss indigenous breeds, infectious hoof disease in zebu is not observed. Therefore, we compared the prevalence of three ruminant hoof pathogens in zebu and taurine cattle.
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- The Mycoplasma Immunoglobulin Binding/Protease (MIB-MIP) system is a virulence factor found in pathogenic Mollicutes, like Mycoplasma feriruminatoris, that helps these bacteria evade the immune system by cleaving host immunoglobulins.
- Research using -omics technologies showed that M. feriruminatoris has four MIB-MIP gene copies with varying expression levels, all transcribed as operons through different promoters.
- Although MIB-MIP proteins can be functionally expressed on the surface of M. feriruminatoris, introducing MIB-MIP systems from other Mollicutes like Mesomycoplasma hyorhinis was unsuccessful, but