Publications by authors named "J Jonckheer"
Background: Alterations in regional brain microcirculation have not been well studied in patients with sepsis. Regional brain microcirculation can be studied using contrast-enhanced brain ultrasound (CEUS) with microbubble administration.
Methods: CEUS was used to assess alterations in regional brain microcirculation on 3 consecutive days in 58 patients with sepsis and within 24 h of intensive care unit admission in 10 aged-matched nonseptic postoperative patients.
Background: Verona integron-encoded metallo-β-lactamase-producing Pseudomonas aeruginosa (VIM-PA) outbreaks are frequently linked to contaminated sink-drains in the intensive care unit (ICU). This study aims to investigate a VIM-PA outbreak occurring at 4 ICUs in a Belgian university center.
Methods: Between 01/01/2019 and 30/07/2023, data were retrospectively retrieved.
Article Synopsis
- Understanding the significance of kidney disease (KD) in hospitalized patients, this guideline aims to provide evidence-based nutritional recommendations due to the metabolic and nutritional impacts of acute (AKD) and chronic kidney disease (CKD).
- The guideline development involved a systematic review of literature from 1999 to 2020, leading to over 30 recommendations on assessing nutritional status, identifying at-risk patients, and integrating nutrition with kidney replacement therapy (KRT) through a consensus process.
- The conclusion emphasizes the diverse nutritional needs of patients with KD, advocating for personalized nutrition strategies to prevent underfeeding and overfeeding, and offering practical advice for daily clinical practice.
Effect of high versus standard protein provision on functional recovery in people with critical illness (PRECISe): an investigator-initiated, double-blinded, multicentre, parallel-group, randomised controlled trial in Belgium and the Netherlands.
Lancet
August 2024
Article Synopsis
- The PRECISe trial aimed to determine if providing critically ill patients on mechanical ventilation with higher protein intake (2.0 g/kg per day) would enhance their quality of life and functional recovery compared to standard protein intake (1.3 g/kg per day).
- This double-blinded, multicentre trial included patients from 10 hospitals across the Netherlands and Belgium, focusing on those expected to need invasive ventilation for at least three days.
- Key aspects of the study included random assignment to either the standard or high-protein group, with blinding of all involved personnel, and tracking the primary outcome through health utility scores at specified intervals (30, 90, and 180 days post-randomization).