Publications by authors named "J Jiricka"

Article Synopsis
  • - In hamster fibroblasts transformed by Rous sarcoma virus (RSV), the PI-3K/Akt pathway is activated, leading to increased protein synthesis through the initiation factor eIF2B.
  • - Inhibition of PI-3K with wortmannin reduces the phosphorylation of p70 S6k and ribosomal protein S6 in non-transformed cells, indicating its role in normal cells.
  • - However, in RSV-transformed cells, PI-3K does not regulate p70 S6k, suggesting that RSV transformation alters the signaling pathway involved in protein synthesis.
View Article and Find Full Text PDF

In the years 1986-1987 the authors operated on 14 patients with 15 fractures in the area of the distal part of the forearm. They performed external fixation in open fractures and in unstable, intra-articular and extra-articular closed fractures. They use Poldi 7 external fixation device, the clamp type of fixation with the insertion of 2 screws into the radius and 2 screws into the second metacarpal.

View Article and Find Full Text PDF

Four mouse myelomas commonly used for cell fusions (X63.Ag8.653, SP2/0, NS1, P3U1), 3 human myeloma-like cell lines (ARH77, U-266, GM1500) and 3 human x mouse hybridomas (SPAZ4, SA2, SA3) were compared for their heterokaryon formation and successful hybridoma growth after cell fusion with polyethylene glycol.

View Article and Find Full Text PDF