Publications by authors named "J Jesse Haddad"
Intra- and Inter-Rater Reliability, Measurement Error and Criteria and Convergent Validities of the Dualpex Plus for the Vaginal Manometry of Pelvic Floor Muscles in Women With Urinary Incontinence.
Neurourol Urodyn
December 2024
Objective: To test the Intra- and inter-rater reliability, measurement error and criteria and convergent validities of the Dualpex Plus (DP) for vaginal manometry in women with urinary incontinence (UI).
Design: This is a clinimetric properties study.
Setting: University Hospital in Brazil.
OSBP ligands from the ORPphilin family are chemically complex natural products with promising anticancer properties. Here, we describe macarangin B, a natural racemic flavonoid selective for OSBP, which stands out from other ORPphilins due to its structural simplicity and distinct biological activity. Using a bioinspired strategy, we synthesized both (,,) and (,,)-macarangin B enantiomers, enabling us to study their interaction with OSBP based on their unique optical properties.
View Article and Find Full Text PDFRelationship Between the PERFECT Scheme, Vaginal Manometry, and Transperineal Ultrasound in Women With and Without Stress Urinary Incontinence: A Cross-Sectional Study.
Int Urogynecol J
December 2024
Article Synopsis
- The study aimed to compare three assessment methods for pelvic floor function—PERFECT scheme, vaginal manometry, and transperineal ultrasound—in women with and without stress urinary incontinence (SUI).
- It involved a cross-sectional analysis of 51 women with SUI and 47 without, evaluating various pelvic floor metrics while excluding those with severe conditions.
- Results showed strong correlations among some measures of the PERFECT scheme and vaginal manometry in the SUI group, but no correlation between ultrasound variables and the other assessment methods.
Objective: 2-Deoxy-2-[F]fluoro-D-glucose ([F]FDG) is widely used for noninvasive imaging of atherosclerosis. However, knowledge about metabolic processes underlying [F]FDG uptake is mostly derived from cell culture studies, which cannot recapitulate the complexities of the plaque microenvironment. Here, we sought to address this gap by mapping of the activity of selected major dehydrogenases involved in glucose metabolism in atherosclerotic plaques.
View Article and Find Full Text PDFObjective: Comparing the efficacy of electrical stimulation (ES) and pelvic floor muscles training (PFMT) on urinary incontinence (UI) symptoms, quality of life and sexual function on women with stress UI. Also, to analyze the influence of supervised and non-supervised PFMT.
Methods: Systematic review of randomized trials involving adult women with stress UI.