Publications by authors named "J Jegu"
Article Synopsis
- A study was conducted to determine the best time frame for considering second primary cancers (SPCs) following a first cancer diagnosis, as current definitions vary widely without clear reasoning. //!
- Researchers analyzed data from 696,775 patients diagnosed with a first cancer between 1989 and 2010, finding a median synchronicity period of about 120.5 days, which translates to approximately 4 months. //!
- The study revealed variations in this synchronicity period based on factors like gender, age, and the type of first cancer, indicating that men tended to take longer to show SPC compared to women. //!
Background: Postoperative stroke is a rare complication after lung cancer surgery but has a high mortality rate. No strategy has been recommended to detect carotid artery disease preoperatively in lung cancer patients. The main objective of this study was to evaluate whether a routine carotid duplex ultrasound (DUS) altered the preoperative management of these patients.
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- Cancer registries collect and manage data on malignant tumors, but as the data volume grows, manual tracking becomes increasingly challenging.
- The study aimed to create an automated system using machine learning to accurately identify and process new cases of prostate adenocarcinoma from various data sources in a French cancer registry.
- The automated model showed high accuracy, achieving over 96% precision and near-perfect recall rates, effectively streamlining the registration process while confirming the findings with a specialized technician.
Background: management of head and neck squamous cell carcinomas (HNSCC) include anti-Epidermal Growth Factor Receptor (EGFR) antibodies and radiotherapy, but resistance emerges in most patients. mutations lead to primary resistance to EGFR blockade in metastatic colorectal cancer but are infrequent in HNSCC, suggesting that other mechanisms are implicated. Since hypoxia and Hypoxia Inducible Factor-1 (HIF-1) have been associated with treatment failure and tumor progression, we hypothesized that EGFR/mammalian Target Of Rapamycin (mTOR)/HIF-1 axis inhibition could radiosensitize HNSCC.
View Article and Find Full Text PDFBackground: Soft tissue sarcomas are rare and heterogenous tumors that are hard to diagnose. The aim of this study was to evaluate local practices and conformity to clinical practice guidelines (CPGs) for their initial diagnostic management.
Materials And Methods: Patients were carriers of a soft tissue or visceral tumor, presented at a sarcoma tumor board (STB) between 2010 and 2016.