Publications by authors named "J Javadpour"

Article Synopsis
  • Surface topography influences cell functions, and current research focuses on methods to regulate stem cell behavior using cell imprinted substrates with micro- and nanoscale structures.
  • The study utilized photolithography to create silicon wafers replicating the shape of chondrocytes and investigated their effects on adipose-derived mesenchymal stem cell differentiation.
  • Results showed that substrates imprinted with chondrocyte shapes promoted chondrogenic differentiation more effectively than standard patterns, highlighting the importance of incorporating nanostructures in engineered substrates for better outcomes.
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3 mol% yttria-stabilized zirconia ceramics have been gaining attention as promising restorative materials that are extensively used in dental implant applications. However, implant failure due to bacterial infection and its bioinert surface slow osseointegration in vivo, which are significant issues in clinical applications. In this work, surface modification was achieved using a continuous wave carbon dioxide laser at a wavelength of 10.

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Background: Solvent casting/particulate leaching is one of the most conventional methods for fabricating polymer/ceramic composite scaffolds. In this method, the solvent generally affects resulting scaffold properties, including porosity and degradation rate.

Methods: Herein, composite scaffolds of PLGA (poly(lactide-co-glycolide))/ nano-hydroxyapatite (nHA) with different percentages of nHA (25, 35, and 45 wt.

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As an alternative for polymethyl methacrylate, poly(propylene fumarate) (PPF) has been considered as injectable and biodegradable bone cement; however, its mechanical and biological properties need more attention. Hence, the current study aimed to develop the properties by compositing PPF with magnesium calcium phosphate (MCP) nano-powders. In this regard, the pure PPF was compared with PPF/MCP by evaluating their composition, mechanical properties, hydrophilicity, and biodegradability.

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This study aimed to produce a composite of poly(propylene fumarate)/magnesium calcium phosphate as a substitutional implant in the treatment of trabecular bone defects. So, the effect of magnesium calcium phosphate particle size, magnesium calcium phosphate:poly(propylene fumarate) weight ratio on compressive strength, Young's modulus, and toughness was assessed by considering effective fracture mechanisms. Micro-sized (∼30 µm) and nano-sized (∼50 nm) magnesium calcium phosphate particles were synthesized via emulsion precipitation and planetary milling methods, respectively, and added to poly(propylene fumarate) up to 20 wt.

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