Publications by authors named "J Januszewski"
Hepatocellular carcinoma (HCC) is the most common liver cancer as well as the most prevalent cause of death in the adult patient population with cirrhosis. The occurrence of HCC is primarily caused by chronic liver inflammation that might occur because of a viral infection, non-alcoholic fatty liver disease (NAFLD), or various lifestyle-associated factors. The objective of this review was to summarize the current knowledge regarding the microenvironment of HCC, indicating how immune- and non-immune-cell stroma might affect the onset and progression of HCC.
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- Obsessive-compulsive disorder (OCD) has different causes, including environmental and genetic factors, but recent research suggests a link between various infections and an increased risk of developing OCD.
- The review examined studies published since 1991 that addressed the connection between specific viruses, bacteria, and parasites, and POCD, highlighting several infectious diseases like Herpes, Rubella, and Toxoplasma as potential contributors.
- While a significant relationship was found between infections and OCD risk, further research is needed to clarify the underlying mechanisms and to explore the impact of other pathogens.
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- Endometrial cancer is a common cancer in women's reproductive health, with rising incidence and mortality, making early diagnosis essential for effective treatment.
- This paper reviews existing literature on the impact of nutritional status, particularly micronutrients and macronutrients, on endometrial cancer patients, focusing on metallomic studies.
- While some nutrients like calcium might reduce risk, and deficiencies in phosphorus, selenium, and zinc may offer protection, excess iron, copper, and cadmium increase risk, pointing to a complex relationship that requires more research to fully understand potential nutritional interventions.
Breast cancer is one of the most common cancers worldwide, at the same time being one of the most prevalent causes of women's death. Many factors such as alcohol, weight fluctuations, or hormonal replacement therapy can potentially contribute to breast cancer development and progression. Another important factor in breast cancer onset includes micronutrient status.
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- Non-alcoholic fatty liver disease (NAFLD) involves fat buildup and liver inflammation, often linked to obesity, insulin resistance, and poor diet.
- This review highlights the importance of understanding nutrient intake and potential supplements like vitamins A, B, C, D, and zinc in managing and treating NAFLD.
- It emphasizes the need for more research on appropriate supplement dosages to effectively support patients with NAFLD.