Publications by authors named "J Jalanka"

Article Synopsis
  • * Findings indicate that mothers who engage in physical activity three or more times a week may significantly reduce their child's risk of developing asthma, with an adjusted odds ratio showing about a 46% lower risk.
  • * The research suggests that increased maternal physical activity could be a valuable preventive measure against asthma in childhood and highlights the need for further investigation in this area.
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Imbalanced microbiota may contribute to the pathophysiology of irritable bowel syndrome (IBS), thus fecal microbiota transplantation (FMT) has been suggested as a potential treatment. Previous studies on the relationship between clinical improvement and microbiota after FMT have been inconclusive. In this study, we used 16S rRNA gene amplicon and shotgun metagenomics data from a randomized, placebo controlled FMT trial on 49 IBS patients to analyze changes after FMT in microbiota composition and its functional potential, and to identify connections between microbiota and patients' clinical outcome.

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Objective: Smoking reduction or cessation are critical public health goals, given the well-documented risks of tobacco use to health. Reducing smoking frequency and cessation entirely are challenging due to nicotine addiction and withdrawal symptoms, which can significantly affect mental wellness and overall wellbeing. Previous research has suggested that certain dietary supplements may support smoking cessation and reduction efforts by mitigating these adverse effects.

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Altered microbiota and impaired host immune function have been linked to the pathogenesis of pouchitis. We used 16S rRNA gene sequencing and RNA sequencing data from a previous randomized clinical trial (RCT) on fecal microbiota transplantation (FMT) therapy in 26 chronic pouchitis patients with one-year follow-up. We analyzed changes in both luminal and mucosal microbiota composition, as well as in host mucosal gene expression to gain insights into the host-microbiota interactions possibly underlying clinical outcomes of the patients.

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Article Synopsis
  • * Researchers analyzed dust samples from the living rooms of 382 homes and tracked the asthma status of children by age 10.5, linking specific fungal genera to asthma outcomes.
  • * The study found differences in fungal composition between homes of asthmatic and non-asthmatic children, but overall, the early-life mycobiota didn't show strong associations with asthma development after considering other factors and adjustments.
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