Multifunctional materials are accelerating the development of soft electronics with integrated capabilities including wearable physical sensing, efficient thermal management, and high-performance electromagnetic interference shielding. With outstanding mechanical, thermal, and electrical properties, nanocarbon materials offer ample opportunities for designing multifunctional devices with broad applications. Surface and interfacial engineering have emerged as an effective approach to modulate interconnected structures, which may have tunable and synergistic effects for the precise control over mechanical, transport, and electromagnetic properties.
View Article and Find Full Text PDFObjectives: To investigate the relationship between physical activity and depressive symptoms in stroke survivors.
Design: A cross-sectional study utilizing National Health and Nutrition Examination Survey (NHANES) 2007-2018 data, employing propensity score matching to control for confounders.
Patients: 1,140 stroke survivors from NHANES, assessing depressive symptoms through the Patient Health Questionnaire-9 (PHQ-9) conducted via family interview or a mobile examination centre examination.
The Rpd3S histone deacetylase complex has a crucial role in genomic integrity by deacetylating transcribed nucleosomes following RNA polymerase (Pol) II passage. Cryo-EM studies highlight the importance of asymmetrical Rco1-Eaf3 dimers in nucleosome binding, yet the interaction dynamics with nucleosomal substrates alongside elongating Pol II are poorly understood. Here we demonstrate the essential function of the Rco1 N-terminal intrinsically disordered region (IDR) in modulating Pol II association, in which K/R mutations within the Rco1 IDR impair interaction of Rpd3S with the C-terminal domain (CTD) of Rpb1, without affecting nucleosome recognition or complex integrity.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
January 2025
Background And Objective: The incidence of central precocious puberty (CPP) in girls increased significantly during the COVID-19 pandemic. This study aimed to explore the impact of perfluorinated endocrine disruptors on CPP through metabolomics analysis in girls from Hainan Province, China.
Methods: Serum samples from 100 girls with CPP and 100 healthy controls were collected.
In this study, gaseous element mercury (GEM) and gaseous oxidized mercury (GOM) in the atmosphere were continuously observed at a minute resolution from 1 April 2019 to 31 December 2020 in urban Xi'an, the largest central city in Northwestern China. The concentrations of GEM and GOM drastically fluctuated within the ranges of 0.022-297 ng/m and 0.
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