Publications by authors named "J J Wykrzykowska"
Deferral of routine percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation: rationale and design of the PRO-TAVI trial: the PRO-TAVI trial: rationale and design.
Am Heart J
December 2024
Background: Concomitant coronary artery disease (CAD) is highly prevalent in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI). The optimal treatment strategy for CAD is a topic of debate. An initial conservative strategy for CAD in patients undergoing TAVI may be favorable as multiple studies have failed to show an evident beneficial effect of percutaneous coronary intervention (PCI) on mortality after TAVI.
View Article and Find Full Text PDFBackground: The Hydra CE study revealed 1-year favorable efficacy of TAVR, showing a large effective orifice area (EOA), low gradient, and acceptable complication rates.
Aims: We evaluated the 3-year clinical and hemodynamic outcomes of Hydra self-expanding transcatheter aortic valve (manufactured by Vascular Innovations Co Ltd, Nonthaburi, Thailand; a subsidiary of Sahajanand Medical Technologies Limited, India) in patients with symptomatic severe aortic stenosis at high or extremely high surgical risk.
Methods: The Hydra CE study was a prospective, multicenter, single-arm study.
Article Synopsis
- - The ACC/AHA Chest Pain guidelines support the use of Coronary CT Angiography (CCTA) and FFRCT for better diagnosing coronary artery disease (CAD), yet many healthcare providers are not following these recommendations.
- - In a study involving 673 stable chest pain patients across five European countries, CCTA emerged as the most frequently used noninvasive test, but nearly 40% of patients still received immediate CAD treatment without prior testing.
- - The study revealed a lack of progress in improving adherence to CCTA and a low usage of FFRCT, underscoring the need for better diagnostic practices and updates to reimbursement policies.
Article Synopsis
- This study investigates how to predict suboptimal quantitative flow ratios (QFR) after successful PCI, as current models are lacking in this area.
- The researchers created a nomogram using data from 450 vessels to evaluate the prediction based on five key variables, including a new metric called QFR-PPG.
- Results showed strong predictive performance with high accuracy in different validation tests, highlighting the nomogram's potential to aid clinicians in making informed decisions post-PCI.
Lipoprotein(a) in interventional cardiology: identifying patients at highest risk of recurrent cardiovascular events through early recognition - a case based review.
Expert Rev Cardiovasc Ther
August 2024
Article Synopsis
- Lipoprotein(a) [Lp(a)] is associated with increased risk for atherosclerotic cardiovascular disease (ASCVD), but there are gaps in its measurement among cardiologists according to current guidelines.
- The review presents four clinical cases showing the link between elevated Lp(a) levels and coronary artery disease (CAD), supported by consensus statements from leading heart organizations.
- Emphasizing routine Lp(a) measurement can help identify high-risk patients, guiding more aggressive treatment and tailored care in catheterization settings, while ongoing clinical trials explore Lp(a)-lowering therapies.