Publications by authors named "J J Wald"
Dimethyl sulfoxide (DMSO) is a widely used solvent in drug research. However, recent studies indicate that even at low concentration DMSO might cause structural changes of proteins and RNA. The pyrazolopyrimidine antiviral OBR-5-340 dissolved in DMSO inhibits rhinovirus-B5 infection yet is inactive against RV-A89.
View Article and Find Full Text PDFComparison of current staging systems for predicting pediatric cholesteatoma outcomes.
Int J Pediatr Otorhinolaryngol
December 2024
Article Synopsis
- This study evaluates the effectiveness of two staging systems (EAONO-JOS and Potsic) in predicting recurrence of cholesteatoma in children with different types (congenital, primary acquired, and secondary acquired).
- Conducted from 2015 to 2023, the research analyzed surgical outcomes from 31 ears in 30 pediatric patients, examining variables like residual disease and factors like stapes erosion that might signal recidivism.
- Results indicated high rates of residual disease, particularly in congenital and primary acquired cases, and found a potential correlation between certain variables and poorer outcomes; however, limitations in the staging systems decreased the predictivity for residual disease.
Background And Purpose: CSF-venous fistulas are a common cause of spontaneous intracranial hypotension. The diagnosis and precise localization of these fistulas hinges on specialized myelographic techniques, which mainly include decubitus digital subtraction myelography and decubitus CT myelography (using either energy integrating or photon counting detector CT). A previous case series showed that cone beam CT myelography, performed as an adjunctive tool with digital subtraction myelography, increased the detection of CSF-venous fistulas.
View Article and Find Full Text PDFArticle Synopsis
- * In a study of 150 patients, 59.3% achieved recovery or were able to receive a durable LVAD or a heart transplant, while 18.8% died within 90 days, indicating a significant success rate compared to mortality.
- * The device significantly improved hemodynamic measurements, such as reduced pulmonary artery diastolic pressure, suggesting better heart function, and even allowed for supporting patients with right ventricle dysfunction through careful monitoring of trends.
Racial, Ethnic, Socioeconomic, and Geographic Inequities in Access to Mechanical Circulatory Support.
J Soc Cardiovasc Angiogr Interv
January 2024
Background: Hospital admissions for cardiogenic shock have increased in the United States. Temporary mechanical circulatory support (tMCS) can be used to acutely stabilize patients. We sought to evaluate the presence of racial, ethnic, and socioeconomic inequities in access to MCS in the United States among patients with cardiogenic shock.
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