Publications by authors named "J J Tegeler"
Article Synopsis
- Thermal noise and hypothermia can affect thermodilution measurement accuracy, which may pose challenges in patients with acute burns.
- This study examined 50 mechanically ventilated burn patients, analyzing 750 thermodilution measurements over 48 hours to assess the reproducibility of hemodynamic parameters.
- Results showed that the reproducibility of cardiac output and blood volume measurements was good (coefficient of variation < 10%), while extravascular lung water had slightly higher variability, but still acceptable, indicating that arterial thermodilution is reliable even in patients with temperature fluctuations.
Background: Ever since Charles Baxter's recommendations the standard regime for burn shock resuscitation remains crystalloid infusion at a rate of 4 ml/kg/% burn in the first 24h following the thermal injury. A growing number of studies on invasive monitoring in burn shock, however, have raised a debate regarding the adequacy of this regime. The purpose of this prospective, randomised study was to compare goal-directed therapy guided by invasive monitoring with standard care (Baxter formula) in patients with burn shock.
View Article and Find Full Text PDFIn neuroleptic long-term medication, only part of the patients accept regular intake of neuroleptic drugs. The question is whether an interval medication regimen as opposed to continuous medication can help to reduce drop outs in patients with critical attitudes towards long-term medication. In a 2-year prospective study, 122 patients were randomised to an interval and 164 to a continuous neuroleptic medication regimen.
View Article and Find Full Text PDFIn a prospective, clinical study, the clinical utility of indocyanine green for intraoperative monitoring of free tissue transfer was evaluated. The study comprised 20 surgical patients undergoing elective microsurgical procedures. Indocyanine green angiography was performed intraoperatively, immediately after flap inset, and the operating team was blind to the fluoremetric findings.
View Article and Find Full Text PDFStudy Objective: Arterial thermal dilution with an integrated fiberoptic monitoring system (COLD Z-021; Pulsion Medical Systems; Munich, Germany) allows measurement of extravascular lung water (EVLW) and pulmonary permeability index (PPI). The aim of this study was to evaluate the widespread clinical assumption that early respiratory failure following burn and inhalation injury is due to interstitial fluid accumulation in the lung.
Design: Clinical, prospective study.