Publications by authors named "J J Reynolds-Wright"

Article Synopsis
  • The study investigated the effectiveness and safety of medication abortion using mifepristone and misoprostol in women up to 42 days of gestation without confirmed intrauterine pregnancy using ultrasound.
  • A total of 1504 women were randomly assigned to either an early-start abortion group or a standard delayed care group, and the primary outcome measured was the rate of complete abortion.
  • The results showed a nearly identical rate of complete abortion between the two groups (95.2% early-start vs 95.3% standard), indicating that starting medication abortion before confirming intrauterine pregnancy is as safe and effective as standard care.
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The concept of a hormonal approach that sufficiently and reversibly suppresses spermatogenesis to the level required for effective contraception has been developed and tested over several decades. The reality of achieving this has been confirmed using both testosterone alone and combination methods using a progestogen with a physiological dose of testosterone, necessary to replace the lack of endogenous testosterone production by the suppressed testes. A range of both long-acting and self-administered combination methods are effective, including injection, implant and gel methods of administration, with up to 95% of men achieving sufficient spermatogenic suppression.

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Background: Most abortions in Scotland are conducted at home before 12 weeks' gestation using telemedicine. The volume of information given at a pre-abortion consultation may feel overwhelming and contraception may not be prioritised. Telemedicine limits immediate provision of some methods.

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