Publications by authors named "J J Presneill"
Objective: To compare the effects of fluid bolus therapy (FBT) with 20% albumin to crystalloid FBT on the incidence of cardiac surgery-associated acute kidney injury (CSA-AKI) and its severity and duration.
Design: Secondary analysis of the multicenter, parallel-group, open-label, randomized HAS FLAIR-II trial.
Setting: Six intensive care units.
Background: The Treatment of Mechanically Ventilated Adults with Early Activity and Mobilisation (TEAM) trial reported a higher occurrence of adverse events with greater mobilisation. However, their timing and nature remained unexplored. We conducted an in-depth exploration of such events.
View Article and Find Full Text PDFBackground: Patients in the intensive care unit (ICU) frequently develop hyperactive delirium, which may be accompanied by behaviour that increases clinical risks to themselves as well as other patients and staff. There is a paucity of evidence to inform the urgent enteral administration of antipsychotic drugs to treat such hyperactive delirium and behavioural disturbances.
Objective: The aim of this study is to test the efficacy and safety of administering enteral olanzapine when compared to quetiapine in critically ill patients with hyperactive delirium.
Missing data and long-term outcomes from nutrition research in the critically ill.
Curr Opin Clin Nutr Metab Care
December 2024
Article Synopsis
- The review highlights the growing importance of using functional outcomes in critical care nutrition research, emphasizing the challenges posed by missing data.
- It points out that ignoring missing data can lead to biased results and suggests proactively estimating the extent and reasons for this missingness.
- The adoption of modern statistical techniques, like multiple imputation and mixed regression models, can enhance the reliability and applicability of research findings in clinical settings.