Publications by authors named "J J Ponte"
Background: Limited data from prospective studies suggest that higher dietary intake of long-chain omega-3 polyunsaturated fatty acids (LCn3PUFA), which hold anti-inflammatory properties, may reduce endometrial cancer risk; particularly among certain subgroups characterized by body mass and tumor pathology.
Materials And Methods: Data from 12 prospective cohort studies participating in the Epidemiology of Endometrial Cancer Consortium were harmonized as nested case-control studies, including 7268 endometrial cancer cases and 26,133 controls. Habitual diet was assessed by food frequency questionnaire, from which fatty acid intakes were estimated.
Article Synopsis
- Researchers created endometrial cancer risk prediction models using data from postmenopausal White women in 19 studies to improve interventions and screenings for this rising cancer risk.
- The models demonstrated modest predictive ability, with area under the curve values (ranging from 0.64 to 0.69), and the addition of genetic factors slightly improved predictions in some cohorts.
- The epidemiologic-based model effectively identified high-risk women but showed variations in performance across different cohorts, indicating a need for refinement and adaptation for diverse populations.
"Non-metastatic, Castration-resistant Prostate Cancer: Diagnostic and Treatment Recommendations by an Expert Panel from Brazil".
Clin Genitourin Cancer
April 2023
Introduction: Non-metastatic, castration-resistant prostate cancer (nmCRPC) is an important clinical stage of prostate cancer, prior to morbidity and mortality from clinical metastases. In particular, the introduction of novel androgen-receptor signaling inhibitors (ARSi) has changed the therapeutic landscape in nmCRPC. Given recent developments in this field, we update our recommendations for the management of nmCRPC.
View Article and Find Full Text PDFBackground: Epidemiologic studies suggest that coffee consumption may be inversely associated with risk of endometrial cancer (EC), the most common gynecological malignancy in developed countries. Furthermore, coffee consumption may lower circulating concentrations of estrogen and insulin, hormones implicated in endometrial carcinogenesis. Antioxidants and other chemopreventive compounds in coffee may have anticarcinogenic effects.
View Article and Find Full Text PDFBackground: Susac syndrome (SS) is a rare endotheliopathy with an estimated prevalence of 0.14-0.024 per 100,000.
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