Publications by authors named "J J Menegazzi"
In patients with out-of-hospital cardiac arrest (OHCA) who attain return of spontaneous circulation (ROSC), rearrest while in the prehospital setting represents a significant barrier to survival. To date, there are limited data to guide prehospital emergency medical services (EMS) management immediately following successful resuscitation resulting in ROSC and prior to handoff in the emergency department. Post-ROSC care encompasses a multifaceted approach including hemodynamic optimization, airway management, oxygenation, and ventilation.
View Article and Find Full Text PDFEvaluating the current breadth of randomized control trials on cardiac arrest: A scoping review.
J Am Coll Emerg Physicians Open
October 2024
Objectives: Despite the significant disease burden due to cardiac arrest, there is a relative paucity of randomized controlled trials (RCTs) to inform definitive management. We aimed to evaluate the current scope of cardiac arrest RCTs published between 2015 and 2022.
Methods: We conducted a search in October 2023 of MEDLINE, Embase, and Web of Science for cardiac arrest RCTs.
Article Synopsis
- - The study investigates the potential for injury during chest compressions (CC) on infants and children, comparing two depth targets: 1.5 inches and 1/3 of the anterior-posterior chest diameter (APD), finding that the latter may lead to more severe injuries.
- - Using an anesthetized swine model, researchers induced asphyxia and delivered CC using both depth targets to assess the resulting injuries, with various factors being monitored and analyzed post-resuscitation.
- - Results from 36 animals showed significant differences in injury characteristics between the two compression depths, prompting further evaluation of safe guidelines for pediatric resuscitation practices.
Revisiting the "Scanty Science" of Prehospital Emergency Care 25 Years Later.
Prehosp Emerg Care
September 2024
Objective: We aimed to quantify the number of prehospital randomized controlled trials (RCTs) published in the 25 years since the Callaham editorial and review his perception of prehospital emergency care as "scanty" science.
Methods: We replicated Callaham's methods to retrieve publications related to prehospital randomized controlled trials (RCTs). This study systematically searched over 35 million citations cataloged by the National Library of Medicine in the PubMed Database between January 1, 1998, and December 31, 2022.
Importance: The incidence of opioid-associated out-of-hospital cardiac arrest (OA-OHCA) has grown from less than 1% of OHCA in 2000 to between 7% and 14% of OHCA in recent years; American Heart Association (AHA) protocols suggest that emergency medical service (EMS) clinicians consider naloxone in OA-OHCA. However, it is unknown whether naloxone improves survival in these patients or in patients with undifferentiated OHCA.
Objective: To evaluate the association of naloxone with clinical outcomes in patients with undifferentiated OHCA.