Publications by authors named "J J Melendez"
Background: Background: This study investigates the effects of cognitive interventions on executive functions and attention in patients with moderate Alzheimer's, comparing traditional and technology-based methods with a control group.
Method: A randomized controlled trial was conducted with 112 participants, divided into three groups: traditional intervention, technology-based intervention, and control group. Sixteen sessions were carried out, assessed using standardized tests and applying hierarchical linear mixed models to adjust for confounding factors and random effects.
Article Synopsis
- The review focuses on episode-based bundled payment models for hand surgery as a means to reduce healthcare costs and improve patient care.
- Traditional fee-for-service models are ineffective in promoting collaboration among healthcare providers, while bundled payments encourage team-based approaches and resource optimization.
- Current literature suggests that implementing these models could lead to cost savings and better patient outcomes, warranting further trials in hand surgery.
Background: Sexually transmitted infections (STIs) are a global health challenge. Testing is not routinely performed in low- and middle-income countries (LMICs), which bear a disproportionate burden of STIs. Self-collected penile-meatal swabs (SCPMS) are an alternative to urine for STI testing, but data from LMICs are limited.
View Article and Find Full Text PDFBackground: Post-harvest physiological deterioration (PPD) poses a significant challenge to the cassava industry, leading to substantial economic losses. This study aims to address this issue by developing a comprehensive framework in collaboration with cassava breeders.
Results: Advanced deep learning (DL) techniques such as Segment Anything Model (SAM) and YOLO foundation models (YOLOv7, YOLOv8, YOLOv9, and YOLO-NAS), were used to accurately categorize PPD severity from RGB images captured by cameras or cell phones.
Article Synopsis
- In 2022, the monkeypox virus outbreak prompted the need for immediate public health responses, leading to the exploration of plant-derived monoclonal antibodies (mAbs) as potential treatments due to their antiviral properties.
- The study specifically focuses on developing a plant-derived mAb that targets the extracellular enveloped virion (EV) of MPXV, which is crucial for the virus's spread and resistant to neutralization.
- The findings confirm that the plant-made mAb, named H2, effectively binds to the MPXV EV and neutralizes it, marking a significant advancement in therapeutic strategies against monkeypox and highlighting the potential of plant-based antibodies for treating emerging infectious diseases.