Publications by authors named "J J Manclus"
Sepsis management remains one of the most important challenges in modern clinical practice. Rapid progression from sepsis to septic shock is practically unpredictable, hence the critical need for sepsis biomarkers that can help clinicians in the management of patients to reduce the probability of a fatal outcome. Circulating nucleoproteins released during the inflammatory response to infection, including neutrophil extracellular traps, nucleosomes, and histones, and nuclear proteins like HMGB1, have been proposed as markers of disease progression since they are related to inflammation, oxidative stress, endothelial damage, and impairment of the coagulation response, among other pathological features.
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- - A photonic biosensor using a bimodal waveguide interferometer (BiMW) was developed to quickly and accurately detect fenitrothion (FN) in tap water, addressing the environmental and health concerns related to pesticide use.
- - The biosensor showed a limit of detection (LOD) of 0.29 ng/mL and could provide results within 20 minutes without needing pretreatment of water samples.
- - Successful tests on blind tap water samples demonstrated high recovery rates, indicating the biosensor's effectiveness for real-time monitoring of water quality.
Spotted wing drosophila, Matsumura (Diptera: Drosophilidae), has become a key pest for soft fruits and cherries in Europe in less than a decade since the first outbreak in 2007. Although this pest's passive dispersal ability has been observed over more than 1400 km in 1 year, active spread has not yet been extensively studied. A mark-release-recapture (MRR) method based on protein-marked flies was employed to determine the flight capacity of .
View Article and Find Full Text PDFFluorescence polarization immunoassays (FPIAs) for thiabendazole and tetraconazole were first developed. Tracers for FPIAs of thiabendazole and tetraconazole were synthesized and the tracers' structures were confirmed by HPLC-MS/MS. The 4-aminomethylfluorescein-labeled tracers allowed achieving the best assay sensitivity and minimum reagent consumption in comparison with aminofluorescein-labeled and alkyldiaminefluoresceinthiocarbamyl-labeled tracers.
View Article and Find Full Text PDFBackground: Tuberculosis, one of the oldest diseases affecting human beings, is still considered as a world public health problem by the World Health Organization.
Method & Material: Therefore, there is a need for new and more powerful analytical methods for early illness diagnosis. With this idea in mind, the development of a High Fundamental Frequency (HFF) piezoelectric immunosensor for the sensitive detection of tuberculosis was undertaken.