High heterogeneity in the size distribution of the micellar fraction from in vitro digestions: sample preparation and reporting recommendations.

Background: Understanding the size and surface charge (ζ-potential) of particles in the mixed micellar fraction produced by in vitro digestion is crucial to understand their cellular absorption and transport. The inconsistent presentation of micellar size data, often limited to average particle diameter, makes comparison of studies difficult. The present study aimed to assess different size data representations (mean particle diameter, relative intensity- or volume-weighted size distribution) to better understand physiological mixed micelle characteristics and to provide recommendations for size reporting and sample handling.

HIV pre-exposure prophylaxis for men who have sex with men in west Africa: a multicountry demonstration study.

Background: HIV pre-exposure prophylaxis (PrEP) data in men who have sex with men (MSM) in west Africa are essential to guide its large-scale implementation. We assessed the uptake of event-driven and daily PrEP, HIV incidence, and changes over time in sexual behaviours and prevalence of bacterial sexually transmitted infections (STIs) in MSM in Burkina Faso, Côte d'Ivoire, Mali, and Togo.

Methods: We did a prospective cohort study from Nov 20, 2017, to April 14, 2020, in four community-based clinics in Abidjan (Côte d'Ivoire), Bamako (Mali), Lomé (Togo), and Ouagadougou (Burkina Faso).

A descriptive study of the use of cardiac point of care ultrasound (PoCUS) in public emergency centres in Cape Town.

Introduction: The indications for cardiac point of care ultrasound (PoCUS) vary somewhat in different parts of the world, and training programs may also differ. We set out to describe the self-reported cardiac PoCUS indications and imaging windows used at a selection of secondary-level, public hospital emergency centres in Cape Town.

Methods: A descriptive study with prospective data collected from emergency centres of Mitchells Plain District, Victoria and New Somerset Hospitals in Cape Town were used.

Inflation of 430-parsec bipolar radio bubbles in the Galactic Centre by an energetic event.

The Galactic Centre contains a supermassive black hole with a mass of four million Suns within an environment that differs markedly from that of the Galactic disk. Although the black hole is essentially quiescent in the broader context of active galactic nuclei, X-ray observations have provided evidence for energetic outbursts from its surroundings. Also, although the levels of star formation in the Galactic Centre have been approximately constant over the past few hundred million years, there is evidence of increased short-duration bursts, strongly influenced by the interaction of the black hole with the enhanced gas density present within the ring-like central molecular zone at Galactic longitude |l| < 0.

Stabilized microwave-frequency transfer using optical phase sensing and actuation.

We present a stabilized microwave-frequency transfer technique that is based on optical phase sensing and optical phase actuation. This technique shares several attributes with optical-frequency transfer and, therefore, exhibits several advantages over other microwave-frequency transfer techniques. We demonstrated the stabilized transfer of an 8000 MHz microwave-frequency signal over a 166 km metropolitan optical fiber network, achieving a fractional frequency stability of 6.