Publications by authors named "J J Lejeune"
Background And Aims: Primary lung tumors (PLTs) in children are rare, and surgery remains the key to ensure remission. Here we describe the PLTs clinical characteristics, their management, and the pulmonary outcome following surgery.
Methods: We carried out a French national cohort of pediatric PLTs from 2013 to 2023 from the FRACTURE rare pediatric tumors national database.
Background: Delivering care that is responsive to who or what is most important to patients and family caregivers is a key aspect of quality care, yet it remains unclear how clinicians can best support individuals in expressing their personal values. We aimed to describe patient- and family caregiver-identified facilitators and barriers to engaging in values discussions with clinicians following implantation of a left ventricular assist device (LVAD).
Methods And Results: Using a qualitative descriptive approach, patients with an LVAD and their caregivers participated in 1-on-1 semistructured interviews and self-reported sociodemographics (January 2023-July 2023).
Impact of socioeconomic factors on time to diagnosis of childhood cancer.
Pediatr Hematol Oncol
February 2025
Article Synopsis
- The study investigates the relationship between socioeconomic status (SES) and time to diagnosis (TTD) in childhood cancer, noting that a clearer connection has been observed in adults.
- A retrospective analysis involving 854 children revealed a median TTD of 28 days, with variations based on tumor type but no significant link between SES factors and TTD.
- Initial treatment by non-specialized professionals was associated with longer TTD, while overall, TTD did not appear to influence children's survival or relapse rates, indicating a need for further research on individual SES impacts.
Article Synopsis
- Hematological involvement (HI) is a serious condition associated with Langerhans cell histiocytosis (LCH), and is defined by low blood cell counts indicating potential life-threatening complications.
- A study of 2,313 children with LCH revealed that about 331 developed HI, with a distinction between mild (MHI) and severe HI (SHI), each showing different health outcomes and survival rates over 10 years.
- Recent advances in treatment have improved mortality rates, particularly with combination therapies and targeted treatments, sparking discussions about refining HI definitions to better inform treatment strategies.