Predicting fall parameters from infant skull fractures using machine learning.

When infants are admitted to the hospital with skull fractures, providers must distinguish between cases of accidental and abusive head trauma. Limited information about the incident is available in such cases, and witness statements are not always reliable. In this study, we introduce a novel, data-driven approach to predict fall parameters that lead to skull fractures in infants in order to aid in determinations of abusive head trauma.

Building the Capacity of Young Professionals in Family Planning to Publish: Insights from the ICFP2022 WHO Scientific Writing, Mentoring and Coaching Course.

Objectives: We describe the development, delivery, and evaluation of a program to support junior professionals to publish their work in a scientific journal.

Study Design: Conference delegates with an accepted abstract at the International Conference on Family Planning (ICFP), self-identifying as junior professionals and from a low- or middle-income country (LMIC) or working predominantly in LMIC settings, were eligible for the program. The program involved: (i) Four face-to-face workshops at ICFP from the 14 to 17 of November 2022; (ii) mentoring meetings at ICFP; (iii) a six-month post-conference online coaching program; and (iv) post-conference learning webinars from December 2022 to May 2023.

Neurosteroid replacement therapy using tiagabine and zuranolone restores cerebellar neurodevelopment and reduces hyperactive behaviour following preterm birth.

Preterm birth exposes the neonate to hypoxic-ischaemic and excitotoxic insults that impair neurodevelopment and are magnified by the premature loss of placentally supplied, inhibitory neurosteroids. The cerebellum is a neuronally dense brain region, which undergoes critical periods of development during late gestation, when preterm births frequently occur. We propose that neurosteroid replacement therapy using tiagabine and zuranolone will protect the cerebellum against preterm-associated insults.

Predictive factors for the diagnosis of coeliac disease in children and young people in primary care: A systematic review and meta-analysis.

Background: Coeliac Disease (CD) often has its onset in childhood and affects 1% of the population. This review aimed to identify important predictive factors for coeliac disease in children and young people which could help GPs decide when to offer testing.

Methods: We searched MEDLINE, Embase and Cochrane Library to April 2024.

Mobile health (mHealth) interventions for health promotion during the perinatal period in India: a scoping review.

Introduction: Perinatal and maternal mortality rates remain high in India compared to global levels, and there is significant heterogeneity in outcomes across Indian states. Many mobile health (mHealth) interventions have been developed to improve maternal and infant health outcomes in India, however it is unclear how mHealth can best support women in this culturally and resource diverse setting. Therefore, we aimed to identify mHealth interventions targeting women and their families in the perinatal period in India, identify barriers and facilitators to their uptake, and future research directions.