Publications by authors named "J J Herrman"

Article Synopsis
  • Coronary artery calcification can hinder the results of procedures like percutaneous coronary intervention (PCI), often leading to stent issues like underexpansion or fractures.
  • The study, called EXIT-CALC, aimed to compare the effectiveness of intravascular lithotripsy (IVL) versus traditional balloon methods in improving stent expansion in severely calcified coronary arteries.
  • Results showed no significant difference in stent expansion between the IVL and conventional groups, and there were no major adverse cardiac events reported during the study period.
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Background: In patients under <40 years, traditional cardiovascular (CV)-risk factors are a less likely cause of acute coronary syndromes (ACS) compared to older counterparts.

Aims: To estimate the prevalence of essential thrombocytosis (ET), a hematological disorder and less-prevalent risk factor, in young patients presenting with ACS.

Methods: We constructed a retrospective database of all patients <40 years (n=271) that had consecutively undergone coronary angiography (CAG) after their  ACS within our hospital within the last ten years (2010-2020) and had known thrombocyte counts (n=241).

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Background: The proprotein convertase subtilisin kexin type-9 inhibitor evolocumab produced coronary atheroma regression in statin-treated patients.

Objectives: The purpose of this study was to determine the effect of evolocumab on optical coherence tomography (OCT) measures of plaque composition.

Methods: Patients with a non-ST-segment elevation myocardial infarction were treated with monthly evolocumab 420 mg (n = 80) or placebo (n = 81) for 52 weeks.

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