Evaluation of electrolyzed water to control fungal trunk pathogens in grapevine nurseries.

Background: Grapevine producers demand solutions to control fungal trunk pathogens (FTPs) in nurseries. Adopting integrated strategies combining several control methods has been indicated as the best approach to prevent or reduce infections on grapevine propagation material. In recent years, electrolyzed water (EW) has emerged as a sustainable alternative for disinfection.

and , in addition to , may cause Phomopsis cane and leaf spot disease in grapevine.

Phomopsis cane and leaf spot (PCLS) disease, affecting grapevines ( and spp.), has been historically associated with . Typical disease symptoms, comprising bleaching and black pycnidia, have also been associated with other spp.

Effect of Temperature on the Development of Fruiting Bodies of and on Grapevine Cuttings In Vitro and Survival of Both Pathogens in Vineyards.

In this study, isolates of and , fungal pathogens associated with Petri and esca diseases of grapevine, were used to determine the effect of temperature on the development of their fruiting bodies in vitro. Perithecia of and pycnidia of were induced at 5, 10, 15, 20, 25, and 30°C on pieces of 1-year-old grapevine cuttings of 110 Richter rootstock, which were incubated for 45 days under continuous white light. Both species were able to produce abundant fruiting bodies at temperatures ranging from 15 to 25°C, but produced more perithecia at 25°C and produced more pycnidia at 20°C.

Integrating gender analysis into research: reflections from the Gender-Net Plus workshop.

Gender equality has been a crosscutting issue in Horizon 2020 with three objectives: gender balance in decision-making, gender balance and equal opportunities in project teams at all levels, and inclusion of the gender dimension in research and innovation content. Between 2017 and 2022, the EU funded, in collaboration with national agencies, 13 transnational projects under "GENDER-NET Plus" that explored how to best integrate both sex and gender into studies ranging from social sciences, humanities, and health research. As the projects neared completion, forty researchers from these interdisciplinary teams met in November 2022 to share experiences, discuss challenges, and consider the best ways forward to incorporate sex and gender in research.

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder.

Sequence variants in the HERC2 gene are associated with a significant reduction in HERC2 protein levels and cause a neurodevelopmental disorder known as the HERC2-related disorder, which shares clinical features with Angelman syndrome, including global developmental delay, intellectual disability, autism, and movement disorders. Remarkably, the HERC2 gene is commonly deleted in individuals with Angelman syndrome, suggesting a potential contribution of HERC2 to the pathophysiology of this disease. Given the known critical role of autophagy in brain development and its implication in neurodevelopmental diseases, we undertook different experimental approaches to monitor autophagy in fibroblasts derived from individuals affected by the HERC2-related disorder.