Publications by authors named "J J Ewbank"
Biomedical data are generated and collected from various sources, including medical imaging, laboratory tests and genome sequencing. Sharing these data for research can help address unmet health needs, contribute to scientific breakthroughs, accelerate the development of more effective treatments and inform public health policy. Due to the potential sensitivity of such data, however, privacy concerns have led to policies that restrict data sharing.
View Article and Find Full Text PDFArticle Synopsis
- - The EOSC-Life consortium aims to enhance data reuse and sustainability in life sciences through collaborative efforts among 13 European research infrastructures, focusing on large-scale and computational research.
- - Key barriers to sustainability identified include organisational, technical, financial, and legal/ethical challenges, which need to be addressed to improve resource management.
- - The initiative advocates for adhering to FAIR principles and promotes data harmonisation and cross-disciplinary training, leading to better interoperability of tools and data in life science research.
Innate immunity is the first line of host defense against pathogens. Here, through global transcriptome and proteome analyses, we uncover that newly described cytoplasmic poly(A) polymerase TENT-5 (terminal nucleotidyltransferase 5) enhances the expression of secreted innate immunity effector proteins in . Direct RNA sequencing revealed that multiple mRNAs with signal peptide-encoding sequences have shorter poly(A) tails in -deficient worms.
View Article and Find Full Text PDF