The impact of hypoalbuminemia on the long-term prognosis of patients with acute heart failure: The modifying role of carbohydrate antigen 125.

Aims: Hypoalbuminemia is frequently found in patients with heart failure (HF), associated with higher morbimortality in acute HF (AHF). Moreover, Carbohydrate Antigen 125 (CA125) is elevated in most of the AHF patients. In this cohort of patients admitted for AHF, our objective was to evaluate the association between hypoalbuminemia and long-term outcomes, including mortality and HF readmissions, stratified by CA125 concentration.

Basic Science and Pathogenesis.

Background: Frontotemporal dementia (FTD) remains one of the most common forms of early-onset dementia (45 to 65 years). FTD consists clinically and pathologically of a heterogeneous group of disorders characterized by progressive frontal and temporal lobe atrophy. Thirty to fifty percent of cases have a family history of the disease.

Mental health indicators in pharmaceutical sciences students during the COVID-19 pandemic.

Introduction: The COVID-19 pandemic changed the daily lives of university students and affected their mental health. The aim of this study was to assess the feelings and perceptions regarding the pandemic and teaching, and to identify the mental health symptoms perceived by pharmaceutical sciences students at a Brazilian public university.

Methods: This is a cross-sectional study with data triangulation (mixed-methods approach), conducted online with semiannual data collection from May 2020 to May 2021.

Reversible Bimetallic Inhibition to Modulate Selectivity During Catalysis.

Bimetallic complexes have demonstrated a great ability to enhance the activity of monometallic systems for bond activation and catalysis. In this work, we explore the opposite approach: using a second metal to passivate the activity of another by reversible bimetallic inhibition. To do so we have synthesized a family of nine electrophilic gold complexes of formula Au(PR)(NTf) ([NTf] = [N(SOCF)]) that can act as inhibitors in the semihydrogenation of terminal and internal alkynes catalyzed by the iconic iridium Vaska complex IrCl(CO)(PPh).

Corrigendum: Familial partial lipodystrophy resulting from loss-of-function PPARγ pathogenic variants: phenotypic, clinical, and genetic features.

[This corrects the article DOI: 10.3389/fendo.2024.