Publications by authors named "J J Caceres"

Objectives: Patients with refractory chronic pain may be considered for spinal cord stimulation (SCS) as an interventional therapy. Studies have shown that psychiatric disorders are associated with worse outcomes. However, this relationship may not be understood by all healthcare professionals.

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Article Synopsis
  • The study proposes a new laser-induced breakdown spectroscopy (LIBS) method for determining bioequivalence of generic drugs in vitro, focusing on the similarity between drug formulations rather than just dissolution performance.
  • This LIBS technique is efficient and straightforward, eliminating the need for complicated sample prep or expensive equipment, allowing direct application on drug samples.
  • The results showed that generic drugs tested were in vitro bioequivalent, meeting the regulatory standards of both American and European medicines agencies, even for drugs with very low active ingredients.
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This article provides a detailed discussion of the evidence available to date on the application of laser-induced breakdown spectroscopy (LIBS) and supervised classification methods for the individual reassignment of commingled bone remains. Specialized bone chemistry studies have demonstrated the suitability of bone elemental composition as a distinct individual identifier. Given the widely documented ability of the LIBS technique to provide elemental emission spectra that are considered elemental fingerprints of the samples analyzed, the analytical potential of this technique has been assessed for the investigation of the contexts of commingled bone remains for their individual reassignment.

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Scientific evidence sustains PM particles' inhalation may generate harmful impacts on human beings' health; therefore, their monitoring in ambient air is of paramount relevance in terms of public health. Due to the limited number of fixed stations within the air quality monitoring networks, development of methodological frameworks to model ambient air PM particles is primordial to providing additional information on PM exposure and its trends. In this sense, this work aims to offer a global easily-applicable tool to estimate ambient air PM as a function of meteorological conditions using a multivariate analysis.

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