Publications by authors named "J J Bustos"
Objective: To conduct a point prevalence survey (PPS) of antibiotic use in the main pediatric tertiary-level hospital in Panama City to establish antibiotic prevalence and identify key areas for addressing antimicrobial resistance.
Methods: This point prevalence survey (PPS) conducted in a tertiary-level hospital in Panama followed the Pan American Health Organization's adaptation of the methodology proposed by the World Health Organization for PPSs on antibiotic use. Information obtained included patients' demographic characteristics, antimicrobial prescriptions, indication for antimicrobial use, and prescription's adherence to guidelines.
Neurocysticercosis (NCC) is caused by the invasion of larvae in the central nervous system (CNS) and stands as the predominant cause of epilepsy and other neurological disorders in many developing nations. NCC diagnosis is challenging because it relies on brain imaging exams (CT or MRI), which are poorly available in endemic rural or resource-limited areas. Moreover, some NCC cases cannot be easily detected by imaging, leading to inconclusive results.
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- An elevated lactate/albumin ratio (LAR) greater than 0.5 in critically ill pediatric patients is linked to higher mortality and microcirculation issues, particularly in children with sepsis.
- In a study involving 178 children admitted to the PICU, those with septic shock showed significantly higher chances of having an elevated LAR and more microvascular blood flow abnormalities.
- The findings suggest that a normal LAR indicates less risk of microcirculatory injury, making LAR a valuable biomarker for assessing sepsis-related complications in pediatric patients.
Background: Cystic echinococcosis (CE) is a widespread neglected zoonotic disease caused by (EG) with a global burden of control in the billions of dollars. life cycle involves definitive, intermediate, and humans as dead-end hosts. Echinococcosis control programs use strategies that focus on any of these hosts.
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- - Neurocysticercosis is a significant parasitic disease, and diagnosing it often requires neuroimaging, which can be hard to access in poor rural areas.
- - A new, quick point-of-care (POC) test was developed to detect urinary antigens, improving diagnosis by identifying individuals who need further imaging.
- - The POC assay showed a 73.6% overall agreement with the standard Ag-ELISA, performing especially well in nonreactive and positive sample groups, making it a practical and noninvasive option for community screening.