Agaricus bisporus mannose-binding protein (Abmb) was discovered as part of the mushroom tyrosinase (PPO3) complex, but its function in the mushroom has remained obscure. The protein has a β-trefoil structure that is common for Ricin-B-like lectins. Indeed, its closest structural homologs are the hemagglutinin components of botulinum toxin (HA-33) and the Ricin-B-like lectin from Clitocybe nebularis (CNL), both of which bind galactose, and actinohivin, a recently discovered mannose-binding lectin from actinomycetes.
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June 2018
Iron and zinc deficiencies are global health problems, affecting mostly pregnant women and young children. In 2016, biofortified iron and zinc beans were introduced in Colombia. The incorporation of biofortified beans into the national school-feeding program could facilitate adoption and potentially improve the nutritional status of large populations.
View Article and Find Full Text PDFA hypothesis, proposed 25 years ago, that there is selection against glycosylation in ruminant pancreatic ribonucleases by replacement of methionine to leucine in the ancestral carbohydrate attachment site Asn-Met-Thr at residues 34-36, was experimentally confirmed. The replacement of leucine at position 35 by methionine in bovine ribonuclease resulted in a three-fold relative increase in glycosylation when expressed in Chinese hamster ovary cells.
View Article and Find Full Text PDFThe visual perception of human movement from sparse point-light walkers is often believed to rely on local motion analysis. We investigated the role of local motion in the perception of human walking, viewed from the side, in different tasks. The motion signal was manipulated by varying point lifetime.
View Article and Find Full Text PDFNonrigid point-light representations of biological motion are ideal to test higher level influences on structure-from-motion (SFM) perception. Here, we investigated the influence of biological motion perception on 3D SFM interpretations at different speeds. We presented nonrigid biological motion and rigid structures rotating around the vertical axis.
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