The condition status index for doline lakes in urban areas.

Karst represents approximately 15% of the planet's surface, hundreds of millions of people live on and rely on these aquifers for water supply and agricultural irrigation. In karstic landscapes, groundwater is exposed in sinkholes, inundated caves, and artesian wells, which are two-way communication spots. When the phreatic level is exposed, the groundwater can change substantially as a result of anthropogenic impacts, modifying the water quality and the environmental integrity by incoming excess nutrients, contaminants, pathogens, and other hazardous substances such as metals and microplastics.

Vaccine-carditis study: Spanish multicenter registry of inflammatory heart disease after COVID-19 vaccination.

Introduction And Objectives: Vaccines against SARS-CoV-2 have been a major scientific and medical achievement in the control of the COVID-19 pandemic. However, very infrequent cases of inflammatory heart disease have been described as adverse events, leading to uncertainty in the scientific community and in the general population.

Methods: The Vaccine-Carditis Registry has included all cases of myocarditis and pericarditis diagnosed within 30 days after COVID-19 vaccination since August 1, 2021 in 29 centers throughout the Spanish territory.

In vitro redox activity of haemozoin and β-haemozoin interacting with the following antimalarials: artemether, lumefantrine and quinine.

Objective: Malaria parasites invade, grow and multiply inside erythrocytes and obtain nourishment from haemoglobin. Then, the released haem group is oxidized to haematin and inert dimeric haemozoin bio-crystals form, which provides the parasite a unique way to avoid the toxicity associated with the haem group. Therefore, antimalarial drugs are designed to inhibit dimer formation; however, recent electrochemical studies indicate that an inert dimer also promotes a toxic oxidizing environment.