Publications by authors named "J J BORRIS"
Introduction: In clinical practice, sublingual (SL) buprenorphine-naloxone is prescribed as once daily or split daily dosing for the management of opioid use disorder (OUD). Evidence is lacking that assesses how split daily buprenorphine-naloxone affects OUD outcomes. This study aims to evaluate how the dosing frequency of SL buprenorphine-naloxone impacts therapy effectiveness when treating patients with OUD.
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- Dry powder inhalers are effective but expensive devices for delivering COPD medications, requiring a peak inspiratory flow rate (PIFR) of at least 30 L/min for effective use.
- A study measured PIFR in hospitalized palliative-care patients with advanced COPD, finding a mean PIFR of 72.5 L/min, indicating that they meet the minimum requirement for inhalation therapy.
- The research suggests that while these patients can effectively use dry powder inhalers, they may struggle to achieve the optimal PIFR of 60 L/min needed for best outcomes.