Publications by authors named "J Ingold"

An 18-year-old male was admitted for his second induction chemotherapy treatment for an acute lymphoblastic leukaemia with cyclophosphamide, cytarabine, and mercaptopurine. He presented with high fever, abdominal pain, non-bloody diarrhoea, portal hypertension and leukopenia. Stool sample analysis, blood cultures and extensive work-up were negative.

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The hepatitis-associated aplastic anemia is one of the acquired bone marrow failure syndromes. It is a stereotyped form of presentation of aplastic anemia and accounts for 2 - 5 % of the cases in the West. Its treatment, which does not differ from that of aplastic anemia, consists of immunosuppression when bone marrow transplant is not possible.

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Article Synopsis
  • - Primary ciliary dyskinesia (PCD) is a rare genetic disorder that affects cilia movement and leads to respiratory issues from birth, but diagnosing it has no standard method and requires specialized tests.
  • - The PCD-UNIBE center in Switzerland developed a thorough diagnostic process including nasal brushing, high-speed videomicroscopy (HSVM), immunofluorescence (IF), and electron microscopy (TEM) to assess patients.
  • - In their assessment of 100 patients, they found that no single diagnostic method was sufficient; 17 patients were confirmed with PCD while others were either inconclusive or ruled out, emphasizing the need for a multi-faceted approach to reliably diagnose the condition.
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Hookworms infection is a soil-transmitted helminthic disease particularly endemic in developing counties of tropical regions. It is attributed mainly to two human pathogens nematodes namely Necator americanus and Ancylostoma duodenale. Although the disease has been characterized as "neglected" is very diffi cult to be eliminated and the economic consequences are great.

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Background: The authors reviewed changes in the initial clinical presentation, management techniques, and patterns of disease recurrence over time (1981-1996) in patients with breast carcinoma treated with breast-conserving therapy (BCT) at a single institution. The goals of the current study were to determine the frequency and use of optimal local and systemic therapy techniques and to evaluate the impact of these changes on treatment efficacy.

Methods: Six hundred seven patients with American Joint Committee on Cancer Stage I or II invasive breast carcinomas treated with BCT at William Beaumont Hospital (Royal Oak, MI) constituted the study population.

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