Efficacy of Split-Thickness Thin Amniotic Membrane Graft for Closure of Refractory or Large Macular Holes.

Purpose: To assess the effectiveness of split-thickness amniotic membrane (SAM) grafts in achieving closure of refractory or large macular holes (MH).

Methods: This retrospective study reviewed data from patients who underwent surgical repair of MHs using SAM grafts between January 2019 and December 2023. Key parameters, including best-corrected visual acuity (BCVA) and MH size, were evaluated both preoperatively and postoperatively.

Protection by natural cholera against later episodes of cholera over 10 years of follow-up in Matlab, Bangladesh: a retrospective cohort study.

Background: Patients with cholera have been shown to be protected against subsequent cholera for 3 years after their initial episode. We aimed to assess protection at 10 years of follow-up.

Methods: In this retrospective cohort study, cohorts of patients treated for cholera (index patients) and contemporaneously selected age-matched individuals without cholera (controls), randomly selected from the population of Matlab, Bangladesh, were assembled between 1990 and 2009 and followed for up to 10 years.

Perspectives on Implementing a Communication Facilitator Intervention from a Critical Care Setting.

Context: Critically-ill patients and their families often experience communication challenges during their ICU stay and across transitions in care. An intervention using communication facilitators may help address these challenges.

Objectives: Using clinicians' perspectives, we identified facilitators and barriers to implementing a communication intervention.

Controlled Synthesis of Perovskite Nanocrystals at Room Temperature by Liquid Crystalline Templates.

Perovskite nanocrystals (PNCs) are promising active materials because of their outstanding optoelectronic properties, which are finely tunable via size and shape. However, previous synthetic methods such as hot-injection and ligand-assisted reprecipitation require a high synthesis temperature or provide limited access to homogeneous PNCs, leading to the present lack of commercial value and real-world applications of PNCs. Here, we report a room-temperature approach to synthesize PNCs within a liquid crystalline antisolvent, enabling access to PNCs with a precisely defined size and shape and with reduced surface defects.

Soybean mitogen-activated protein kinase GmMPK6 enhances drought tolerance.

Soybeans are a critical crop that provides both protein and oil. In response to environmental stresses, mitogen-activated protein kinases (MPKs) play a key role in transmitting stress signals to the nucleus to initiate stress-responsive actions. Drought stress reduces plant development and productivity but the specific MPK responsible for drought stress responses has not been previously identified.