Publications by authors named "J Ignacio Aguinalde Saenz"
Gendered Marital Power, Depression, and Cognition Among Older Adults in Mexico.
J Gerontol B Psychol Sci Soc Sci
December 2024
Article Synopsis
- * Using data from the Mexican Health and Aging Study, the research analyzes how actors' (individuals') and partners' (spouses') perceptions of marital power relate to cognitive performance over time, with an emphasis on depression as a mediating factor.
- * Results indicate that lower marital power is associated with decreased cognition, especially for husbands, while women's marital power imbalances lead to higher depression rates for both partners, suggesting a significant link between marital dynamics and cognitive health in older adults.
All cells are encapsulated by a lipid membrane that facilitates their interactions with the environment. How cells manage diverse mixtures of lipids, which dictate membrane property and function, is experimentally challenging to address. Here, we present an approach to tune and minimize membrane lipid composition in the bacterium Mycoplasma mycoides and its derived 'minimal cell' (JCVI-Syn3A), revealing that a two-component lipidome can support life.
View Article and Find Full Text PDFAll cells are encapsulated by a lipid membrane which facilitates the interaction between life and its environment. How life exploits the diverse mixtures of lipids that dictate membrane property and function has been experimentally challenging to address. We introduce an approach to tune and minimize lipidomes in and the Minimal Cell (JCVI-Syn3A) revealing that a 2-component lipidome can support life.
View Article and Find Full Text PDFSurface availability of the dopamine (DA) transporter (DAT) critically influences DA transmission. Here, we present a protocol that describes the preparation of mouse ventral midbrain neurons, the expression of a new optical sensor, DAT-pHluorin, and the utilization of this sensor to analyze the surface availability of DAT in live neurons via fluorescent microscopy. This approach allows quantitative measures of basal surface DAT fraction under genetic backgrounds of interest and live trafficking of DAT in response to psychoactive substances.
View Article and Find Full Text PDFIntroduction: People with dementia can have many family and friends who might be affected by their deaths. Pursuing the long-term aim of understanding how dementia deaths affect close family and friends, this project lays groundwork through estimates of who those close family and friends are, with special attention to race and ethnicity.
Method: Regression models estimated associations between dementia, race/ethnicity, and close family and friend network size, controlling for age, sex, education, marital status, and household wealth for 1386 deceased people with dementia from the Health and Retirement Study (2004 to 2018).