Publications by authors named "J Iannos"

Purpose: The subgroup of patients with venous ulcers requiring anticoagulation for co-morbid conditions has traditionally created a therapeutic dilemma. Perioperative management of anticoagulation can be costly and increase the risk of surgical complications. This group of patients is often elderly and shows poor compliance with compression hosiery.

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Objective: To perform a more critical assessment of infrainguinal vein bypass.

Summary Background Data: Graft patency may give an unrealistic impression of the outcome of bypass surgery.

Methods: During a 6-year period, 236 patients undergoing primary vein grafts were entered into the study.

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In an attempt to predict early graft occlusion secondary to poor distal run-off, the outflow resistance was measured intra-operatively and compared with the intra-operative angiogram in 50 patients undergoing lower limb bypass procedures. With arterial inflow occluded, 60 mL of plasmalyte was infused via a catheter and the resultant pressure generated in the graft was measured through a second catheter connected to a pressure transducer and recorder. Using the infusion rate and integrated pressure value, outflow resistance was calculated.

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The effects of cholecystokinin octapeptide (CCK-OP) on the gall-bladder (GB) and sphincter of Oddi (SO) of the Australian brush tailed possum were examined in 45 anaesthetized animals. CCK-OP (20-640 ng/kg) consistently caused the GB to contract in a dose-dependent manner (Kruskal Wallis P less than 0.05).

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Sphincter of Oddi motility was evaluated in post-cholecystectomy patients with indwelling T tubes during fasting and after feeding. A triple-lumen catheter was positioned to record from the sphincter of Oddi and duodenum. The sphincter of Oddi was characterized by phasic contractions independent of duodenal contractions.

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