Publications by authors named "J I Staubitz"
Objective: Children and adolescents with intellectual and developmental disabilities (IDD), particularly those with autism spectrum disorder, are at increased risk of challenging behaviors such as self-injury, aggression, elopement, and property destruction. To mitigate these challenges, it is crucial to focus on early signs of distress that may lead to these behaviors. These early signs might not be visible to the human eye but could be detected by predictive machine learning (ML) models that utilizes real-time sensing.
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- Intraoperative neuromonitoring (IONM) is crucial for preventing nerve damage during thyroid and parathyroid surgeries, but current data lacks quality measures to remove errors before analysis.
- The authors created the Mainz IONM Quality Assurance and Analysis tool in R, which helps visualize, correct, and analyze raw data from IONM, enabling better reference values for nerve latency and amplitude.
- Analysis of IONM data from 1,935 patients revealed a high incidence of labeling errors, and the tool identified new reference latencies for various nerves, highlighting the need for improved data quality in neuromonitoring.
Article Synopsis
- The study aimed to connect the genetic mutations in papillary thyroid carcinoma with the aggressiveness of the disease to improve surgical treatment recommendations.
- The analysis included 171 patients, revealing a notable prevalence of BRAF-V600E mutations and significant correlations between certain mutations and adverse clinical outcomes, such as increased risk of distant metastasis and radioiodine-refractory disease.
- Findings suggest that patients with both BRAF and TERT promoter mutations should be considered for more aggressive treatment strategies, while RET rearrangements were linked to more lymph node involvement but did not impact metastasis or radioiodine resistance.
[Current indications and operative strategy for renal hyperparathyroidism].
Chirurgie (Heidelb)
July 2023
Background: Renal hyperparathyroidism results from pathophysiologic changes induced and maintained by terminal renal failure. Surgical treatment is possible using various resection strategies.
Aim Of The Work (research Question): The aim of this work is to illustrate the indications, techniques and resection strategies for surgical treatment of renal hyperparathyroidism.
In thyroid surgery, intra-operative neuromonitoring signals of the recurrent laryngeal nerve can be detected by surface electrodes on a tracheal tube positioned at the vocal fold level. The incidence of difficult tracheal intubation in patients undergoing thyroidectomy for nodular goitre ranges from 5.3% to 20.
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