Sarcopenia Predicts Outcomes After Lung Transplantation in Older Lung Transplant Candidates.

Background: As lung transplantation (LT) expands to older recipients, objective approaches to evaluate the aging are needed to optimize posttransplantation outcomes. Frailty assessment and sarcopenia have shown promise as tools for predicting clinical outcomes.

Methods: Patients older than 55 years undergoing evaluation for LT were enrolled in an institutional review board-approved study.

Biomarkers.

Background: Diabetes, a chronic metabolic disease leading to damage to multiple organs and the nervous system, is associated with cognitive decline. Moreover, Vitamin D (VD) insufficiency/deficiency is implicated as a risk factor for diabetes. However, the specifics of the relationships between these variables remain unclear.

Developing Topics.

Background: In the past decades, the NIH has identified a large knowledge gap in the study of health and disease in diverse and underserved inhabitants. The most recent estimates (2020) indicate that rural dwellers represent 15-20% of the total US population, but these individuals experience worse health status than urban counterparts. A major challenge to the study of health disparities in rural areas is the dearth of structured rural cohorts that can be used for scientific research purposes.

Alzheimer's Imaging Consortium.

Background: Our studies show that the small non-coding RNA, mir20a-3p, is neuroprotective for stroke in the acute phase and also attenuates long term cognitive decline in middle-aged female rats. Cognitive decline due to vascular diseases, such as stroke, is associated with secondary neurodegeneration in cortex and limbic structures. In this study, we assessed the volume of white matter, ventricles and regional diffusion-weighted MR imaging measures to delineate pathological tissue characteristics from the postmortem brain of stroke rats.

Perceptions of Crime Severity and Stigma Toward Family Members Grieving the Loss of a Person to Incarceration.

Family members of incarcerated persons may experience grief related to the incarceration. We examined laypeople's perceptions of family members grieving the loss of an individual to incarceration. Participants ( = 1,095) were randomized to read vignettes that varied by grief trajectory (prolonged vs.